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- Team D. Lévy. Functional and structural analysis of membrane proteins
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- concentration wave of E. coli bacteria in a microchannel
- Amphiphilic Poly(ethylene oxide)-block-poly(butadiene-graft-liquid crystal) Copolymers: Synthesis and Self-Assembly in Water
- Binding, reconstitution and 2D crystallization of membrane or soluble proteins onto functionalised lipid layer observed in situ
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- Fig 4. Model of biomolecular networks under duplication-divergence evolution
- Fig 4. Model of biomolecular networks under duplication-divergence evolution
- Fig 5. Expansion of signaling networks by whole genome duplication
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- Fig. 1 Oscillations de moteurs moléculaires
- Expansion of signaling networks by whole genome duplication
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- Functional and structural analysis of BmrC/BmrD abacterial heterodimeric MDR transporter
- Functional and structural analysis of BmrC/BmrD bacterial heterodimeric MDR transporter
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- 2D crystals of BmrC/BmrD
- 2D crystals of BmrC/BmrD, a bacterial heterodimeric ABC transporter
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- Atomic Model of LH1-RC-PufX from Rba. sphaeroides
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- 2D crystals of Light Harversting Complex, LH2, from Rba. sphaeroides
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- 3D reconstruction of LH1-RC-PufX, 280 kDa, at 12 A resolution
- 2D crystals of Light Harversting Complex, LH2, from Rba. sphaeroides
- schematic model of the coupling between the non equivalent catalytic sites of ABC transporters
- schematic model of the coupling between the non equivalent catalytic sites of ABC transporters
- schematic model of the coupling between the equivalent catalytic sites of ABC transporters
- Tubular to planar membranes upon conformational changes of BmrA, a ABC transporter
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fig4
Enhancement of JunB expression in response to membrane tension inhibits BMP2 endocytosis.
The images show immunofluorescence microscopy of BMP2 (a and b) and JunB (c and d) in a mouse myoblast cell line, C2C12. (a) After 10 mins of endocytosis, the signalling protein BMP2 has accumulated inside the cell. (b) Increased membrane tension induced by osmotic shock blocks BMP2 endocytosis and, after 10 mins, the protein remains on the cell surface. (c) BMP2-dependent expression of JunB in cell nuclei 30 mins after incubation of the cells with BMP2. (d) Increased expression of JunB in cell nuclei 30 mins after inhibiting endocytosis by osmotic shock and incubating the cells with BMP2. Blocking endocytosis prevents the internalisation and degradation of BMP2 and thus increases signalling by the BMP2-bound receptor on the cell surface, so stimulating JunB expression.